Biopharma Business

Cancer Biology

New Precision Medicine Centre of Excellence Will Improve Patient Treatment

    New Precision Medicine Centre of Excellence Will Improve Patient Treatment

A £10 million Centre of Excellence in Precision Medicine has been launched by Invest Northern Ireland and Queen’s University Belfast. The Centre of Excellence in Precision Medicine will develop an

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Anti-Pancreatic Cancer Drug In Research Focus

    Anti-Pancreatic Cancer Drug In Research Focus

Intriguing antitumor activity is found in a very promising class of natural compounds: cyclic depsipeptides, which have a challenging structure that makes their investigation difficult. Now, Chinese scientists have established

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Tarloxitinib puts tumour-seeking tail on anti-EGFR drug to target lung cancer

    Tarloxitinib puts tumour-seeking tail on anti-EGFR drug to target lung cancer

EGFR is a common genetic target in lung cancer, but not all EGFR mutations are created equal. Patients with a type of EGFR anomaly called an “EGFR exon 20 insertion”

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Lilly signs up to cancer vaccines with CureVac deal

    Lilly signs up to cancer vaccines with CureVac deal

Eli Lilly has signed up CureVac to develop cancer vaccines based on its mRNA technology, in a deal that could potentially be worth more than $2.6 billion to the German

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NIH launches $215m partnership for cancer immunotherapy strategies

    NIH launches $215m partnership for cancer immunotherapy strategies

The NIH and 11 leading biopharmaceutical companies have launched the Partnership for Accelerating Cancer Therapies (PACT), totalling $215m as part of the Cancer Moonshot… The National Institutes of Health (NIH)

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CEL-SCI receives new European patent for investigational immunotherapy

    CEL-SCI receives new European patent for investigational immunotherapy

The European Patent Office has issued a new patent to biotechnology company, CEL-SCI, for its lead investigational immunotherapy, which is undergoing a Phase III clinical trial for head and neck

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Most approved oncology drugs do not offer better survival rate or quality of life, say researchers

    Most approved oncology drugs do not offer better survival rate or quality of life, say researchers

A retrospective cohort study, published in the British Medical Journal, has found no conclusive evidence that most oncology treatments approved for use by the European Medicines Agency (EMA) offered survival

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Alcohol aversion drug Disulfiram may combat chemotherapy resistance

    Alcohol aversion drug Disulfiram may combat chemotherapy resistance

Scientists have had positive results from a laboratory-based study using a well-known alcohol aversion drug disulfiram, to combat chemotherapy resistance in the most common type of lung cancer, non-small cell

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Successor to PD-1 inhibitors the focus of cancer immunotherapy

    Successor to PD-1 inhibitors the focus of cancer immunotherapy

The cancer immunotherapy pipeline, displays a high level of first-in-class innovation with novel developments focusing heavily on producing the next big immune checkpoint inhibitor, according to GBI Research. GBI Research’s

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UK’s NICE approves Roche’s breast cancer drug Kadcyla for routine use

    UK’s NICE approves Roche’s breast cancer drug Kadcyla for routine use

The UK National Institute for Health and Care Excellence (NICE) has granted approval for Roche’s breast cancer drug Kadcyla for routine use within the NHS region. NICE has recommended Kadcyla

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A drink a day may increase risk of breast cancer, new report reveals

    A drink a day may increase risk of breast cancer, new report reveals

World Cancer Research Fund International has released a new report that demonstrates an increased risk of breast cancer is associated with even moderate alcohol consumption. In the report, a research

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Clinigen, Tesaro partner to supply ovarian cancer drug in Europe

    Clinigen, Tesaro partner to supply ovarian cancer drug in Europe

  Clinigen Group’s Idis Managed Access division and Tesaro have partnered to launch a Managed Access Program (also known as an Early Access Program) in Europe for niraparib, the investigational

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Pfizer gifts the NHS with breast cancer drug

Pfizer has announced it will provide its breast cancer drug, palbociclib — which has been provisionally rejected by NICE for routine use as a result of cost — to the

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Norway Brings Another Cancer Vaccine to the Clinic

Targovax has recruited its first patient in a Phase Ib trial for its new cancer vaccine TG02 targeting mutations of the RAS gene. Mutations of the RAS gene disrupt normal cell

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BTG receives CE mark certification for radiopaque drug-eluting bead

BTG, a global specialist healthcare company, has received Class III CE Mark certification for DC Bead LUMI, the first commercially available radiopaque drug-eluting bead (DEB) in the EU which can

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Novartis’ lung cancer drug combination receives EU approval

The European Commission has approved Novartis’ Tafinlar (dabrafenib) in combination with Mekinist (trametinib) for the treatment of patients with BRAF V600-positive advanced or metastatic non-small cell lung cancer (NSCLC). The

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Anti-cancer drug gets a boost when combined with antirheumatic

Scientists at EPFL and NTU have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy. One

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EMA Recommends Approval of New Treatment for Brain Cancer

Apeiron Biologics has announced that the EMA’s CHMP has recommended the approval of APN311 for immunotherapy of high risk neuroblastoma. Apeiron Biologics is a Vienna-based biotech company developing immunological approaches

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British Biotech’s Breast Cancer Drug gets FDA Approval for Novartis

Novartis has received FDA approval for Kisqali, a first-line treatment for breast cancer originally developed by the British biotech Astex Pharmaceuticals. The oncology company Astex Pharmaceuticals, located in Cambridge’s biotech hub, entered

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Antioxidants and lung cancer risk

An epidemiological study published in Frontiers in Oncology suggests that a diet high in carotenoids and vitamin C may protect against lung cancer. The study authors found that vitamin C

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Price drops make more cancer drugs routinely available

The National Institute for Health and Care Excellence (NICE) is half way through a review of drugs approved and still available only through the old Cancer Drugs Fund (CDF). In

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Actelion gets EU Approval to Launch a Treatment for a Rare Skin Cancer

Actelion has received approval from the European Commission for Ledaga, a treatment to prevent the progression of a rare form of skin cancer. After being acquired by Johnson & Johnson

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New research to help detect oesophageal cancer earlier

A new method to help diagnose oesophageal cancer is being researched by engineers and physicians at the Institute of Biological

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Mundipharma to launch Mabthera biosimilar in EU markets

Mundipharma is gearing up to launch biosimilar Truxima in seven European markets for the treatment of certain cancers and inflammatory

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European Commission conditionally approves Roche’s cancer drug Alecensa

Roche’s oral ALK inhibitor, Alecensa, has been conditionally approved in the European Union as a monotherapy for anaplastic lymphoma kinase-positive

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Emory scientists map ‘spiderweb’ of lung cancer proteins to snare new drug targets

Scientists at Emory University’s Winship Cancer Institute are on a mission to unlock the mysteries of lung cancer cells that

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Tumor-targeting system uses cancer’s own mechanisms to betray its location

By hijacking a cancer cell’s own metabolism, researchers have found a way to tag and target elusive cancers with small-molecule

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New biomarkers for bowel cancer treatment

One of Europe’s largest collaborative academic-industry research projects, designed to develop and assess novel approaches for identification of new markers

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New drug for treatment of aggressive breast cancer found by Irish researchers

As recently published in the International Journal of Cancer, researchers from Breast-Predict, may have found a new drug for the

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